Rho Nutrition Liposomal Methylfolate 5-MTHF + B12 Complex (30 Servings)

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Rho Nutrition Liposomal Methylfolate 5-MTHF + B12 Complex delivers bioactive folate (5-MTHF) and methylcobalamin (B12) in a convenient liquid liposomal formula designed to support absorption. This daily wellness supplement provides 30 servings per bottle and features active forms of two essential B vitamins.
  • 5 mg L-Methylfolate (5-MTHF) per serving
  • 1,000 mcg Methylcobalamin (Vitamin B12) per serving
  • Advanced liposomal delivery technology
  • Liquid supplement format
  • Active forms of folate and B12
  • Orange Pineapple flavor
  • 30 servings per bottle
  • Third-party tested
  • Easy daily dosing
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  • cGMP Facility

    cGMP Facility

  • FDA Inspected Facility

    FDA Inspected Facility

  • 0 Calories per Serving

    0 Calories per Serving

  • Gluten Free

    Gluten Free

  • Non-GMO Lipids

    Non-GMO Lipids

  • Keto Friendly

    Keto Friendly

  • Third-Party Tested

    Third-Party Tested

  • Soy Free

    Soy Free

  • Sugar Free

    Sugar Free

  • Vegan Friendly

    Vegan Friendly

Pharmalynk Pro-Tip

Pair Rho Nutrition Liposomal 5-MTHF + B12 Complex with Rho Nutrition Liposomal TMG to create a comprehensive methylation-focused wellness stack. Many customers use both products together as part of their daily nutrition routine.

*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Rho Nutrition Liposomal Methylfolate 5-MTHF + B12 Complex (30 Servings)

Rho Nutrition Liposomal Methylfolate 5-MTHF + B12 Complex (30 Servings)

RHO Liposomal Technology

RHO Liposomal Technology

Liposomal delivery is a technique used to help support the absorption and bioavailability of certain nutrients. It involves encapsulating the active ingredient within tiny lipid-based bubbles called liposomes. These liposomes act as protective carriers, helping the nutrient pass through the digestive system and supporting its absorption into the body. Traditional supplements break down in digestion. Our phosphatidylcholine-based liposomes act as protective carriers, supporting absorption.

Methylation & Homocysteine Support

Methylation & Homocysteine Support

Supports healthy methylation processes throughout the body, including DNA synthesis, neurotransmitter production, and detoxification pathways.*​

Cardiovascular Health

Cardiovascular Health

Supports cardiovascular function through healthy homocysteine metabolism and maintenance of healthy blood vessels. Essential for heart health and circulation.*

Energy Production & Metabolism

Energy Production & Metabolism

Both folate and B12 play critical roles in cellular energy production and the metabolism of fats, proteins, and carbohydrates. Supports sustained energy and metabolic efficiency throughout the day.*​

Nervous System & Cognitive Function

Nervous System & Cognitive Function

Supports healthy nervous system structure and function, promotes cognitive performance, mental clarity, and healthy neurotransmitter synthesis including serotonin, dopamine, and norepinephrine.*​

Mood & Mental Well-Being

Mood & Mental Well-Being

Supports healthy mood and emotional balance through neurotransmitter synthesis and methylation pathways. Research shows methylfolate and methyl B12 may support mental wellness when used as part of a comprehensive approach.*​

Frequently asked questions

Find clear, helpful answers to the most common questions about Rho Nutrition Liposomal Methylfolate 5-MTHF + B12 Complex (30 Servings).

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Methylfolate (5-MTHF) is the active, bioavailable form of folate that your body can use immediately. Unlike synthetic folic acid, it does not require conversion by your body through the MTHFR enzyme. This makes it ideal for individuals who want more direct support for methylation, mood, homocysteine metabolism, cellular energy, and nervous system health.*
Methyl B12 (methylcobalamin) works synergistically with methylfolate in key methylation pathways that influence neurotransmitter production, DNA synthesis, red blood cell formation, and energy metabolism.*
Taking both together supports efficient methylation and balanced homocysteine levels.*
Each bottle contains 30 servings. When taken daily as directed, it will last 30 days.
Take 6 mL (just over one teaspoon) per day, or as recommended by your healthcare practitioner. You can take it directly from the spoon or mix it into cold water or juice.
Before opening: Store in a cool, dry place.
After opening: While its not required, some people like to refrigerate for taste and freshness.
Use within 75 days of opening.
Liposomal delivery encapsulates nutrients inside tiny phospholipid spheres that help protect them during digestion and support efficient absorption. This system helps your body utilize more of the active forms of folate and B12 where they’re needed most - at the cellular level.*
Genetic variations such as MTHFR can reduce the body’s ability to convert folic acid and standard B12 into their active forms. Because this formula provides pre-methylated nutrients (5-MTHF + methylcobalamin), it bypasses several conversion steps and may offer more consistent support for people who need help with folate and B12 metabolism.* That said, we always recommend consulting a licensed healthcare provider for any medical questions or personal guidance.
This formula supports:
Healthy methylation*
Cellular energy & metabolism*
Nervous system health & cognitive function*
Mood & emotional well-being*
Cardiovascular & homocysteine support*
Benefits vary by individual and depend on overall health, nutritional status, and consistency of use.
Methylated B vitamins are generally well tolerated. Occasionally, some people may feel more energized than expected or notice mild changes in sleep or mood when starting methylated forms. If you are sensitive to methyl donors, consider starting with a smaller amount and increasing as tolerated, or speak with your clinician.
Yes. All Rho products are designed to work synergistically. Methylfolate and B12 pair well with glutathione, magnesium, and other daily essentials. If you take prescription medications or have a medical condition, consult your healthcare professional before starting.
Absolutely. Every batch undergoes rigorous third-party testing for identity, purity, potency, and contaminants. All Rho products are produced in a cGMP-certified, FDA-registered facility with full quality documentation.
Yes. All Rho products are manufactured in an allergen-free, non-GMO, gluten-free, soy-free, dairy-free, and nut-free facility.

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About Rho Nutrition
Transforming wellness with science.
Rho Nutrition liquid vitamins utilize advanced Liposomal technology to ensure superior absorption and benefits, delivering potent nutrients directly to your body's cells. Experience a truly health-optimized life with Rho's cutting-edge supplements.
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